Driving Ability Under Long-Term Treatment with Transdermal Fentanyl

TAVT score. The number of mistakes in the testing of tachistoscopic perception showing significant non-inferiority in the intent-to-treat (ITT) group as well as in the per-protocol-group (PP) compared to the control group (ITT: P = 0.004; PP: P = 0.003). Results of the control group are shown as raw values.

Sum score. Sum score of the z-transformed DT, COG, and TAVT, representing the cognitive items of the test battery. The PP-group was shown to be significantly non-inferior to the control group (P = 0.036); the ITT group did not differ significantly from the control group (P = 0.188). The full circles represent the mean score plus the calculated delta as described in the method section. The values of the control group of the ITT- and the PP-group differ due to the different samples used in the z-transformation.

Percentage of passed tests. The percentage of patients who passed the five tests (i.e., scored above the 16th percentile) showed no difference between the ITT-, PP- and control groups (ITT-group: n = 30 in DT, COG and TAVT; n = 29 in 2-Hand and VIG; PP-group: n = 21 in DT, COG and TAVT; n = 20 in 2-Hand and VIG; Control-group: n = 90 in all tests).