Journal of Pain and Symptom Management
Volume 35, Issue 5 , Pages 563-567 , May 2008

Opioids for Cancer Breakthrough Pain: A Pilot Study Reporting Patient Assessment of Time to Meaningful Pain Relief

  • Giovambattista Zeppetella, FRCP

      Affiliations

    • Corresponding Author InformationAddress correspondence to: Giovambattista Zeppetella, FRCP, St. Clare Hospice, Hastingwood Road, Hastingwood, Essex CM17 9JX, United Kingdom.

,Accepted 29 June 2007.

References 

  1. Portenoy RK, Payne D, Jacobsen P. Breakthrough pain: characteristics and impact in patients with cancer pain. Pain. 1999;81:129–134
  2. Fortner BV, Demarco G, Irving G, et al. Description and predictors or direct and indirect costs of pain reported by cancer patients. J Pain Symptom Manage. 2003;25:9–18
  3. Caraceni A, Martini C, Zecca E, et al. Breakthrough pain characteristics and syndromes in patients with cancer pain: an international survey. Palliat Med. 2004;18:177–183
  4. Bennett D, Burton AW, Fishman S, et al. Consensus panel recommendations for the assessment and management of breakthrough pain. Part 2. Management. P & T. 2005;30:354–361
  5. Ripamonti C, De Conno F, Groff L, et al. Equianalgesic dose/ratio between methadone and other opioid agonists in cancer pain: comparison of two clinical experiences. Ann Oncol. 1998;9:79–83
  6. Laverty D, Davies A. Assessment. In:  Davies A editors. Cancer-related breakthrough pain. Oxford: Oxford University Press; 2006;p. 23–30
  7. Portenoy R, Taylor D, Messina J, Tremmel L. A randomized, placebo-controlled study of fentanyl buccal tablet for breakthrough pain in opioid-treated patients with cancer. Clin J Pain. 2006;22:805–811
  8. Fisher K, Stiles C, Hagen NA. Characterization of the early pharmacodynamic profile of oral methadone for cancer-related breakthrough pain: a pilot study. J Pain Symptom Manage. 2004;28:619–625
  9. Dworkin RH, Turk DC, Farrar JT, et al. Core outcome measures for chronic pain clinical trials: IMMPACT recommendations. Pain. 2005;113:9–19
  10. Zeppetella G, Ribeiro MDC. Opioids for the management of breakthrough (episodic) pain in cancer patients. The Cochrane Database of Systematic Reviews. 2006;Issue 1. Art. No.: CD004311
  11. Hanks GW, De Conno F, Cherny N, et al. Morphine and alternative opioids in cancer pain: the EAPC recommendations. Br J Cancer. 2001;84:587–593

PII: S0885-3924(07)00750-6

doi: 10.1016/j.jpainsymman.2007.06.012

Journal of Pain and Symptom Management
Volume 35, Issue 5 , Pages 563-567 , May 2008

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