Journal of Pain and Symptom Management
Volume 35, Issue 6 , Pages 632-643 , June 2008

Trajectories of Fatigue in Men with Prostate Cancer Before, During, and After Radiation Therapy

  • Christine Miaskowski, RN, PhD, FAAN

      Affiliations

    • University of California, San Francisco
    • Corresponding Author InformationAddress correspondence to: Christine Miaskowski, RN, PhD, FAAN, Department of Physiological Nursing, University of California, 2 Koret Way – Box 0610, San Francisco, CA 94143-0610, USA.
    • ,
  • Steven M. Paul, PhD

      Affiliations

    • University of California, San Francisco
    • ,
  • Bruce A. Cooper, PhD

      Affiliations

    • University of California, San Francisco
    • ,
  • Kathryn Lee, RN, PhD, FAAN

      Affiliations

    • University of California, San Francisco
    • ,
  • Marylin Dodd, RN, PhD, FAAN

      Affiliations

    • University of California, San Francisco
    • ,
  • Claudia West, RN, MS

      Affiliations

    • University of California, San Francisco
    • ,
  • Bradley E. Aouizerat, PhD

      Affiliations

    • University of California, San Francisco
    • ,
  • Patrick S. Swift, MD

      Affiliations

    • Alta Bates Comprehensive Cancer Center, Berkeley, California, USA
    • ,
  • William Wara, MD

      Affiliations

    • University of California, San Francisco

,Accepted 30 July 2007.

  • Image Result

    Trajectories of evening and morning fatigue over the 25 weeks of the study.

    Trajectories of evening and morning fatigue over the 25 weeks of the study.

  • Image Result

    Spaghetti plot of the 82 patients' individual trajectories of evening fatigue (a) and a plot of ten individual evening fatigue trajectories (b) over the 25 weeks of the study.

    Spaghetti plot of the 82 patients' individual trajectories of evening fatigue (a) and a plot of ten individual evening fatigue trajectories (b) over the 25 weeks of the study.

  • Image Result

    Trajectories of evening fatigue by age (i.e., younger/older), level of sleep disturbance at baseline (i.e., low sleep/high sleep), and level of evening fatigue at baseline (i.e., low fatigue/high fati

    Trajectories of evening fatigue by age (i.e., younger/older), level of sleep disturbance at baseline (i.e., low sleep/high sleep), and level of evening fatigue at baseline (i.e., low fatigue/high fatigue).

  • Image Result
    Trajectories of morning fatigue by lower level of depression at baseline (i.e., LOW CES-D) and by age (i.e., younger/older), level of sleep disturbance at baseline (i.e., low sleep/high sleep), and le

    Trajectories of morning fatigue by lower level of depression at baseline (i.e., LOW CES-D) and by age (i.e., younger/older), level of sleep disturbance at baseline (i.e., low sleep/high sleep), and level of morning fatigue at baseline (i.e., low fatigue/high fatigue).

  • Image Result
    Trajectories of morning fatigue by higher level of depression at baseline (i.e., HIGH CES-D) and by age (i.e., younger/older), level of sleep disturbance at baseline (i.e., low sleep/high sleep), and

    Trajectories of morning fatigue by higher level of depression at baseline (i.e., HIGH CES-D) and by age (i.e., younger/older), level of sleep disturbance at baseline (i.e., low sleep/high sleep), and level of morning fatigue at baseline (i.e., low fatigue/high fatigue).

 This research was supported by a grant from the National Institute of Nursing Research (NR04835). Additional support for the corresponding author's program of research was provided through unrestricted grants from Endo Pharmaceuticals, PriCara, Unit of Ortho-McNeil, Inc., and Purdue Pharma LP.

PII: S0885-3924(08)00051-1

doi: 10.1016/j.jpainsymman.2007.07.007

Journal of Pain and Symptom Management
Volume 35, Issue 6 , Pages 632-643 , June 2008

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