Journal of Pain and Symptom Management
Volume 36, Issue 1 , Pages 29-38 , July 2008

Relief of Incident Dyspnea in Palliative Cancer Patients: A Pilot, Randomized, Controlled Trial Comparing Nebulized Hydromorphone, Systemic Hydromorphone, and Nebulized Saline

  • Margaret A. Charles, PhD

      Affiliations

    • School of Psychology, Sydney University, Sydney, New South Wales
    • Corresponding Author InformationAddress correspondence to: Margaret A. Charles, PhD, School of Psychology A18, University of Sydney, NSW 2006, Australia.
    • ,
  • Liz Reymond, MBBS(Hons), PhD, FAChPM

      Affiliations

    • Brisbane South Palliative Care Collaborative, Mt. Olivet Hospital, Brisbane, Queensland, Australia
    • ,
  • Fiona Israel, MCouns

      Affiliations

    • Brisbane South Palliative Care Collaborative, Mt. Olivet Hospital, Brisbane, Queensland, Australia

,Accepted 31 August 2007.

  • Image Result

    Flow of patients through the study. NH-nebulized hydromorphone; SH-systemic hydromorphone; NS-nebulized saline.

    Flow of patients through the study. NH-nebulized hydromorphone; SH-systemic hydromorphone; NS-nebulized saline.

  • Image Result

    Mean breathlessness with treatments: NH=nebulized hydromorphone, SH=systemic hydromorphone, NS=nebulized saline.

    Mean breathlessness with treatments: NH=nebulized hydromorphone, SH=systemic hydromorphone, NS=nebulized saline.

  • Image Result

    (a) Respiratory rate, (b) pulse rate, (c) peripheral oxygen saturation. Objective indicators of respiratory status across treatments and time periods. NH=nebulized hydromorphone, SH=systemic hydromorp

    (a) Respiratory rate, (b) pulse rate, (c) peripheral oxygen saturation. Objective indicators of respiratory status across treatments and time periods. NH=nebulized hydromorphone, SH=systemic hydromorphone, NS=nebulized saline.

 This study was funded by the Sisters of Charity, Mt. Olivet Community Hospice Services, Brisbane, Queensland, Australia. The authors have no conflicts of interest to declare.

PII: S0885-3924(08)00066-3

doi: 10.1016/j.jpainsymman.2007.08.016

Journal of Pain and Symptom Management
Volume 36, Issue 1 , Pages 29-38 , July 2008

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