Journal of Pain and Symptom Management
Volume 38, Issue 6 , Pages 882-893 , December 2009

Symptom Experience in HIV-Infected Adults: A Function of Demographic and Clinical Characteristics

  • Kathryn A. Lee, RN, PhD

      Affiliations

    • Department of Family Health Care Nursing, University of California, San Francisco, California, USA
    • Corresponding Author InformationAddress correspondence to: Kathryn A. Lee, RN, PhD, Department of Family Health Care Nursing, Box 0606, University of California, San Francisco, 2 Koret Way, Room N415Y, San Francisco, CA 94143-0606, USA.
  • ,
  • Caryl Gay, PhD

      Affiliations

    • Department of Family Health Care Nursing, University of California, San Francisco, California, USA
  • ,
  • Carmen J. Portillo, RN, PhD

      Affiliations

    • Community Health Systems, University of California, San Francisco, California, USA
  • ,
  • Traci Coggins, BS

      Affiliations

    • Department of Family Health Care Nursing, University of California, San Francisco, California, USA
  • ,
  • Harvey Davis, RN, PhD

      Affiliations

    • School of Nursing, San Francisco State University, San Francisco, California, USA
  • ,
  • Clive R. Pullinger, PhD

      Affiliations

    • Department of Physiological Nursing, University of California, San Francisco, California, USA
    • Cardiovascular Research Institute, University of California, San Francisco, California, USA
  • ,
  • Bradley E. Aouizerat, PhD

      Affiliations

    • Department of Physiological Nursing, University of California, San Francisco, California, USA
    • Institute for Human Genetics, University of California, San Francisco, California, USA

,Accepted 14 May 2009.

References 

  1. Centers for Disease Control and Prevention. HIV/AIDS surveillance report. Available from: http://www.cdc.gov/hiv/topics/surveillance/. Accessed August 3, 2008.
  2. Harding R, Molloy T. Positive futures? The impact of HIV infection on achieving health, wealth and future planning. AIDS Care. 2008;20:565–570
  3. Harding R, Molloy T, Easterbrook P, Frame K, Higginson IJ. Is antiretroviral therapy associated with symptom prevalence and burden?. Int J STD AIDS. 2006;17:400–405
  4. Breitbart W, McDonald MV, Rosenfeld B, Monkman ND, Passik SD. Fatigue in ambulatory AIDS patients. J Pain Symptom Manage. 1998;15:159–167
  5. Vogl D, Rosenfeld B, Breitbart W, et al. Symptom prevalence, characteristics, and distress in AIDS outpatients. J Pain Symptom Manage. 1999;18:253–262
  6. Gallagher AM, Thomas JM, Hamilton WT, White PD. Incidence of fatigue symptoms and diagnoses presenting in UK primary care from 1990 to 2001. J R Soc Med. 2004;97:571–575
  7. Ladwig KH, Muhlberger N, Walter H, et al. Gender differences in emotional disability and negative health perception in cardiac patients 6 months after stent implantation. J Psychosom Res. 2000;48:501–508
  8. Naqvi TZ, Rafique AM, Andreas V, et al. Predictors of depressive symptoms post-acute coronary syndrome. Gend Med. 2007;4:339–351
  9. Simren M, Svedlund J, Posserud I, Bjornsson ES, Abrahamsson H. Predictors of subjective fatigue in chronic gastrointestinal disease. Aliment Pharmacol Ther. 2008;28:638–647
  10. Bursch B, Lester P, Jiang L, Rotheram-Borus MJ, Weiss R. Psychosocial predictors of somatic symptoms in adolescents of parents with HIV: a six-year longitudinal study. AIDS Care. 2008;20:667–676
  11. Kang S-Y, Goldstein MF, Deren S. Gender differences in health status and care among HIV-infected minority drug users. AIDS Care. 2008;20:1146–1151
  12. Rollman GB. Sex makes a difference: experimental and clinical pain responses. Clin J Pain. 2003;19:204–207
  13. Passik SD, Kirsh KL, Donaghy KB, Portenoy RK. Pain and aberrant drug-related behaviors in medically ill patients with and without histories of substance abuse. Clin J Pain. 2006;22:173–181
  14. Portenoy RK, Thaler HT, Kornblith AB, et al. The Memorial Symptom Assessment Scale: an instrument for the evaluation of symptom prevalence, characteristics and distress. Eur J Cancer. 1994;30A(9):1326–1336
  15. Blinderman CD, Homel P, Billings A, Portenoy RK, Tennstedt SL. Symptom distress and quality of life in patients with advanced congestive heart failure. J Pain Symptom Manage. 2008;35:594–603
  16. Sawicki GS, Sellers DE, Robinson WM. Self-reported physical and psychological symptom burden in adults with cystic fibrosis. J Pain Symptom Manage. 2008;35:372–380
  17. Brechtl JR, Breitbart W, Galietta M, Krivo S, Rosenfeld B. The use of highly active antiretroviral therapy (HAART) in patients with advanced HIV infection: impact on medical, palliative care, and quality of life outcomes. J Pain Symptom Manage. 2001;21:41–51
  18. Lee KA, Portillo CJ, Miramontes H. The fatigue experience for women with human immunodeficiency virus. J Obstet Gynecol Neonatal Nurs. 1999;28:193–200
  19. Lee KA, Portillo C, Miramontes H. The influence of sleep and activity patterns on fatigue in women with HIV/AIDS. J Assoc Nurses AIDS Care. 2001;12(Supplement, 2001):19–27
  20. Wilson IB, Cleary PD. Clinical predictors of functioning in persons with acquired immunodeficiency syndrome. Med Care. 1996;34:610–623
  21. Reid S, Dwyer J. Insomnia in HIV infections: a systematic review of prevalence, correlates, and management. Psychosom Med. 2005;67:260–269
  22. Rubinstein ML, Selwyn PA. High prevalence of insomnia in an outpatient population with HIV infection. J Acquir Immune Defic Syndr. 1998;19:260–265
  23. Leserman J, Barroso J, Pence BW, Salahuddin N, Harmon JL. Trauma, stressful life events and depression predict HIV-related fatigue. AIDS Care. 2008;20:1258–1265
  24. National Sleep Foundation . Omnibus Sleep in America Poll. Washington, DC: National Sleep Foundation; 2000;Available from: www.sleepfoundation.org/articles/sleep-topics/women-and-sleep. Accessed August 3, 2008
  25. Cohen FL, Ferrans CE, Vizgirda V, Kunkle V, Cloninger L. Sleep in men and women infected with human immunodeficiency virus. Holist Nurs Pract. 1996;10:33–43
  26. Solano JP, Gomes B, Higginson IJ. A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease. J Pain Symptom Manage. 2006;31:58–69
  27. Sjogren P, Ekholm O, Peuckmann V, Gronbaek M. Epidemiology of chronic pain in Denmark: an update. Eur J Pain. 2009;13:287–292
  28. Nicholas PK, Voss JG, Corless IB, et al. Unhealthy behaviours for self-management of HIV-related peripheral neuropathy. AIDS Care. 2007;19:1266–1273
  29. Sarna L, van Servellen G, Padilla G, Brecht ML. Quality of life in women with symptomatic HIV/AIDS. J Adv Nurs. 1999;30:597–605
  30. Zingmond DS, Kilbourne AM, Justice AC, et al. Differences in symptom expression in older HIV-positive patients: the Veterans Aging Cohort 3 Site Study and HIV Cost and Service Utilization Study experience. J Acquir Immune Defic Syndr. 2003;33(Suppl 2):S84–S92
  31. Silverberg MJ, Jacobson LP, French AL, Witt MD, Gange SJ. Age and racial/ethnic differences in the prevalence of reported symptoms in human immunodeficiency virus-infected persons on antiretroviral therapy. J Pain Symptom Manage. 2009;38:197–207
  32. Coleman CL. Spirituality and sexual orientation: relationship to mental well-being and functional health status. J Adv Nurs. 2003;43:457–464
  33. Coleman CL, Holzemer WL, Eller LS, et al. Gender differences in use of prayer as a self-care strategy for managing symptoms in African Americans living with HIV/AIDS. J Assoc Nurses in AIDS Care. 2006;17:16–23
  34. Humphreys J, Lee KA, Carrieri-Kohlman V, et al. A middle range theory of symptom management. In:  Smith MJ,  Liehr PR editor. Middle range theory for nursing. 2nd ed.. New York: Springer Publishing Company; 2008;p. 145–158
  35. Hudson A, Portillo C, Lee KA. Sleep disturbances in women with HIV or AIDS: efficacy of a tailored sleep promotion intervention. Nurs Res. 2008;57:360–366
  36. Wisniewski AB, Apel S, Selnes OA, et al. Depressive symptoms, quality of life, and neuropsychological performance in HIV/AIDS: the impact of gender and injection drug use. J NeuroVirol. 2005;11:138–143

 This research was supported by a grant from the National Institute of Mental Health (NIMH 5R01 MH074358). Data collection was supported by the General Clinical Research Center in the UCSF CTSA (1 UL RR024131). Dr. Aouizerat is also supported by an NIH Roadmap K12 (KL2 RR024130), and Dr. Davis is supported by an NIH Research Infrastructure in Minority Institutions (RIMI) award (5P20 MD0005444).

PII: S0885-3924(09)00735-0

doi: 10.1016/j.jpainsymman.2009.05.013

Journal of Pain and Symptom Management
Volume 38, Issue 6 , Pages 882-893 , December 2009