Journal of Pain and Symptom Management
Volume 38, Issue 6 , Pages 816-826 , December 2009

Is Short-Term Palliative Care Cost-Effective in Multiple Sclerosis? A Randomized Phase II Trial

  • Irene J. Higginson, BMedSci, BMBS, PhD, FFPM, FRCP

      Affiliations

    • Department of Palliative Care, Policy and Rehabilitation, King's College London, London, United Kingdom
    • Department of Palliative Care, King's College Hospital, London, United Kingdom
    • Corresponding Author InformationAddress correspondence to: Irene J. Higginson, BMed Sci, BMBS, PhD, FFPM, FRCP, Department of Palliative Care, Policy and Rehabilitation, King's College London School of Medicine, Weston Education Centre, Cutcombe Road, London SE5 9RJ, United Kingdom.
    • ,
  • Paul McCrone, BSc Hons, MSc, PhD

      Affiliations

    • Institute of Psychiatry, King's College London, London, United Kingdom
    • ,
  • Sam R. Hart, BA

      Affiliations

    • Department of Palliative Care, Policy and Rehabilitation, King's College London, London, United Kingdom
    • ,
  • Rachel Burman, MA, FRCP

      Affiliations

    • Department of Palliative Care, Policy and Rehabilitation, King's College London, London, United Kingdom
    • Department of Palliative Care, King's College Hospital, London, United Kingdom
    • ,
  • Eli Silber, MD, FCP(Neuro)SA

      Affiliations

    • Department of Neurology, King's College Hospital, London, United Kingdom
    • ,
  • Polly M. Edmonds, MBBS, MRCP, FRCP

      Affiliations

    • Department of Palliative Care, Policy and Rehabilitation, King's College London, London, United Kingdom
    • Department of Palliative Care, King's College Hospital, London, United Kingdom

,Accepted 13 July 2009.

  • Image Result

    CONSORT diagram showing the flow of patients through the study. N (N)=patients remaining in study (interviews actually completed at this stage). A small number of interviews were missed because the pa

    CONSORT diagram showing the flow of patients through the study. N (N)=patients remaining in study (interviews actually completed at this stage). A small number of interviews were missed because the patient was unavailable (away/in hospital) and one error in scheduling.

  • Image Result
    Cost-effectiveness analysis at 0–12 weeks for PCT compared with control for (A) POS-8 and (B) ZBI. Dots to the right of the axis indicate improved outcomes; dots below the horizontal axis show lower c

    Cost-effectiveness analysis at 0–12 weeks for PCT compared with control for (A) POS-8 and (B) ZBI. Dots to the right of the axis indicate improved outcomes; dots below the horizontal axis show lower costs. Therefore, dots in the lower right quadrant show both improved outcomes and lower costs, and those in the upper left quadrant show worse outcomes and higher costs.

 This study was funded by the Multiple Sclerosis Society of Great Britain and Northern Ireland.

 Clinical Trial Registration: www.ClinicalTrials.gov, Identifier: NCT00364936.

PII: S0885-3924(09)00741-6

doi: 10.1016/j.jpainsymman.2009.07.002

Journal of Pain and Symptom Management
Volume 38, Issue 6 , Pages 816-826 , December 2009

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