Journal of Pain and Symptom Management
Volume 39, Issue 5 , Pages 859-871 , May 2010

Cancer-Related Symptom Clusters, Eosinophils, and Survival in Hepatobiliary Cancer: An Exploratory Study

  • Jennifer L. Steel, PhD

      Affiliations

    • Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    • Corresponding Author InformationAddress correspondence to: Jennifer L. Steel, PhD, University of Pittsburgh School of Medicine; 3459 Fifth Avenue; Pittsburgh, PA 15213, USA.
    • ,
  • Kevin H. Kim, PhD

      Affiliations

    • Department of Psychology in Education, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    • ,
  • Mary Amanda Dew, PhD

      Affiliations

    • Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    • ,
  • Mark L. Unruh, MD

      Affiliations

    • Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    • ,
  • Michael H. Antoni, PhD

      Affiliations

    • Department of Psychology, University of Miami, Miami, Florida, USA
    • ,
  • Marion C. Olek, MS, MPH

      Affiliations

    • University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    • ,
  • David A. Geller, MD

      Affiliations

    • Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    • ,
  • Brian I. Carr, MD, PhD, FRCP

      Affiliations

    • Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    • ,
  • Lisa H. Butterfield, PhD

      Affiliations

    • Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    • Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    • Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    • ,
  • T. Clark Gamblin, MD

      Affiliations

    • Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

,Accepted 16 October 2009.

  • Image Result

    Percent of patients reporting pain, fatigue, and sadness from diagnosis to six months.

    Percent of patients reporting pain, fatigue, and sadness from diagnosis to six months.

  • Image Result

    Cumulative survival of patients with vascular invasion. Eosinophils greater than and less than median of sample.

    Cumulative survival of patients with vascular invasion. Eosinophils greater than and less than median of sample.

  • Image Result

    Cumulative survival of patients without vascular invasion. Eosinophils greater than and less than median of sample.

    Cumulative survival of patients without vascular invasion. Eosinophils greater than and less than median of sample.

 This study was funded by grants from the American Cancer Society, the Pittsburgh Mind Body Center (National Institutes of Health grants HL065111, HL065112, HL076852, and HL076858), and the National Cancer Institute (5K07CA118576).

PII: S0885-3924(10)00142-9

doi: 10.1016/j.jpainsymman.2009.09.019

Journal of Pain and Symptom Management
Volume 39, Issue 5 , Pages 859-871 , May 2010

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