Journal of Pain and Symptom Management
Volume 39, Issue 5 , Pages 839-846 , May 2010

A Comparison of Quality-of-Life Domains and Clinical Factors in Ovarian Cancer Patients: A Gynecologic Oncology Group Study

Presented at the Society of Gynecologic Oncologists 2008 Annual Meeting, Tampa, FL, March 9–12, 2008.

  • Vivian E. von Gruenigen, MD

      Affiliations

    • Department of Reproductive Biology, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    • Corresponding Author InformationAddress correspondence to: Vivian E. von Gruenigen, MD, Department of Reproductive Biology, Division of Gynecologic Oncology, University Hospitals Case Medical Center, Case Western Reserve University, Room 7128, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
    • ,
  • Helen Q. Huang, MS

      Affiliations

    • Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Buffalo, New York, USA
    • ,
  • Karen M. Gil, PhD

      Affiliations

    • Department of Obstetrics and Gynecology, Akron General Medical Center, Akron, Ohio, USA
    • Northeastern Ohio Universities Colleges of Medicine, Rootstown, Ohio, USA
    • ,
  • Heidi E. Gibbons, MS

      Affiliations

    • Department of Reproductive Biology, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    • ,
  • Bradley J. Monk, MD

      Affiliations

    • Chao Family Comprehensive Cancer Center, University of California-Irvine Medical Center, Orange, California, USA
    • ,
  • Peter G. Rose, MD

      Affiliations

    • Department of Obstetrics & Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    • ,
  • Deborah K. Armstrong, MD

      Affiliations

    • Department of Gynecology & Obstetrics, Johns Hopkins University, Baltimore, Maryland, USA
    • ,
  • David Cella, PhD

      Affiliations

    • Center on Outcomes Research and Education, Evanston, Illinois, USA
    • Evanston Northwestern Healthcare and Northwestern University Medical School, Evanston, Illinois, USA
    • ,
  • Lari Wenzel, PhD

      Affiliations

    • Department of Medicine, University of California-Irvine Medical Center, Orange, California, USA
    • Center for Health Policy Research, University of California-Irvine Medical Center, Orange, California, USA

,Accepted 16 October 2009.

References 

  1. Cella DF, Tulsky DS, Gray G, et al. The Functional Assessment of Cancer Therapy (FACT) scale: development and validation of the general measure. J Clin Oncol. 1993;11:570–579
  2. Webster K, Cella D, Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: properties, applications, and interpretation. Health Qual Life Outcomes. 2003;1:79
  3. Brucker PS, Yost K, Cashy J, Webster K, Cella D. General population and cancer patient norms for the functional assessment of cancer therapy-general (FACT-G). Eval Health Prof. 2005;28:192–211
  4. Holzner B, Kemmler G, Cella D, et al. Normative data for function assessment of cancer therapy—general scale and its use for the interpretation of quality of life scores in cancer survivors. Acta Oncol. 2004;43:153–160
  5. Donaldson GW, Moinpour CM. Individual differences in quality-of-life treatment response. Med Care. 2002;40:39–53
  6. Gil KM, Gibbons HE, Jenison EL, Hopkins MP, von Gruenigen VE. Baseline characteristics influencing quality of life in women undergoing gynecologic oncology surgery. Health Qual Life Outcomes. 2007;5:25
  7. Wenzel L, Vergote I, Cella D. Quality of life in patients receiving treatment for gynecologic malignancies: special considerations for patient care. Int J Gynaecol Obstet. 2003;83(Suppl 1):211–229
  8. von Gruenigen VE, Gil KM, Huang H, et al. Assessment of factors that contribute to decreased quality of life in Gynecologic Oncology Group ovarian cancer trials. Cancer. 2009;115:4857–4864
  9. Wenzel L, Huang HQ, Monk BJ, Rose PG, Cella D. Quality-of-life comparisons in a randomized trial of interval secondary cytoreduction in advanced ovarian carcinoma: a Gynecologic Oncology Group study. J Clin Oncol. 2005;23:5605–5612
  10. Wenzel LB, Huang HQ, Armstrong DK, Walker JL, Cella D Gynecologic Oncology Group. Health-related quality of life during and after intraperitoneal versus intravenous chemotherapy for optimally debulked ovarian cancer: a Gynecologic Oncology Group study. J Clin Oncol. 2007;25:437–443
  11. Armstrong DK, Bundy B, Wenzel L, et al. Gynecologic Oncology Group Intraperitoneal cisplatin and paclitaxel in ovarian cancer. N Engl J Med. 2006;54:34–43
  12. Rose PG, Nerenstone S, Brandy MF, et al. Secondary surgical cytoreduction for advanced ovarian carcinoma. N Engl J Med. 2004;351:2489–2497
  13. Basen-Engquist K, Bodurka-Bevers D, Fitzgerald MA, et al. Reliability and validity of the Functional Assessment of Cancer Therapy—Ovarian. J Clin Oncol. 2001;19:1809–1817
  14. Fairclough DL, Cella DF. Functional Assessment of Cancer Therapy (FACT-G): non-response to individual questions. Qual Life Res. 1996;5:321–329
  15. Cella D, Hahn E, Dineen K. Meaningful change in cancer-specific quality of life scores: differences between improvement and worsening. Qual Life Res. 2002;11:207–221
  16. Yost KJ, Eton DT. Combining distribution- and anchor-based approaches to determine minimally important differences. Eval Health Prof. 2005;28:172–191
  17. Vickers AJ. Statistical considerations for use of composite health-related quality-of-life scores in randomized trials. Qual Life Res. 2004;13:717–723
  18. Wan GJ, Counte MA, Cella DF, et al. An analysis of the impact of demographic, clinical, and social factors on health-related quality of life. Value Health. 1999;2:308–318
  19. Movsas B, Scott C, Watkins-Bruner D. Pretreatment factors significantly influence qualify of life in cancer patients: a Radiation Therapy Oncology Group (RTOG) analysis. Int J Radiat Oncol Biol Phys. 2006;65:830–835
  20. Coughlin SS. Surviving cancer or other serious illness: a review of individual and community resources. CA Cancer J Clin. 2008;58:60–64
  21. Wenzel LB, Donnelly JP, Fowler J, et al. Resilience, reflection and residual stress in ovarian cancer survivorship: a Gynecologic Oncology Group study. Psychooncology. 2002;11:142–153

 This work was supported by National Cancer Institute grants to the Gynecologic Oncology Group (GOG) Administrative Office (CA 27469) and the GOG Statistical and Data Center (CA 37517).

PII: S0885-3924(10)00157-0

doi: 10.1016/j.jpainsymman.2009.09.022

Journal of Pain and Symptom Management
Volume 39, Issue 5 , Pages 839-846 , May 2010

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