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Abstract
Occasionally, terminally ill patients with severe agitated dilirium are extremely difficult to sedate, either becoming too deeply sedated when undisturbed or severely agitated when disturbed. This situation occurs even with the short-acting benzodiazepines such as midazolam. This paper discribes the use of a low-dose infusion of the anesthetic agent propofol (Diprivan, Zenica), which has a very short length of action and allows the depth of sedation to be easily controlled from minute to minute.
Keywords
References
- Park GR Sedation and analgesia in the critical care management. Saunders, London1993: 209-225
- A pilot study to compare the use of propofol and midazolam for long term sedation.J Drug Dev. 1989; 2 (suppl 2): 71-72
- A comparison of propofol and midazolam for long-term sedation of ventilated patients: a cross-over study.J Drug Dev. 1989; 2 (suppl 2): 45-47
- Prolonged sedation with propofol in ICU patients: recovery and blood concentrations and changes during periodic interruptions in infusion.Br J Anaesth. 1988; 61: 583-588
Article info
Publication history
Accepted:
April 19,
1995
Identification
Copyright
© 1995 Published by Elsevier Inc.
