Palliative care rounds| Volume 10, ISSUE 8, P643-646, November 1995

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The use of propofol in palliative medicine

  • John Moyle
    Address reprint requests to: John Moyle, MB, BS, FRCA, The Hospice of Our Lady and St. John, Willen Village, Milton Keynes, MK15 9AB, United Kingdom
    The Hospice of Our Lady and St. John, Willen Village, Milton Keynes, United Kingdom
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      Occasionally, terminally ill patients with severe agitated dilirium are extremely difficult to sedate, either becoming too deeply sedated when undisturbed or severely agitated when disturbed. This situation occurs even with the short-acting benzodiazepines such as midazolam. This paper discribes the use of a low-dose infusion of the anesthetic agent propofol (Diprivan, Zenica), which has a very short length of action and allows the depth of sedation to be easily controlled from minute to minute.



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