The life of a physician-scientist is fast paced, at many times exhausting and simultaneously exhilarating. Never-ending demands, both from our work and personal lives, make it challenging to take the time necessary to reflect on where we are, how we arrived here, and where we are ultimately headed. Then, in a flash, something earth-shattering happens to us or someone we care about. In those moments, when life makes the least sense, we are forced to pause. The news of a terminal diagnosis for our beloved mentor, Randy Curtis, was one such moment.